Testing for Concordance Ordering

PAIRED COMPARISON DESIGNS FOR TESTING CONCORDANCE BEl '

Ordering multigene testing in polyneuropathy.

Technological advances allow the assessments of multiple genes, e.g., via next-generation sequencing, in a relatively cost-effective manner. As the ability to assess up to thousands of genes by ordering one test becomes more available, determining which genes should be tested, and when in the workup, needs to be determined. In the article by Wang et al. in this issue of Neurology®, the authors ...

Extreme Unit Testing: Ordering Test Cases to Maximize Early Testing

eXtreme programmingTM is one of several lightweight software development methodologies. It involves extremely short incremental release cycles, early and frequent testing, heavy use of design refactoring, and pair programming. Although early and frequent testing is very important, there is little guidance to date in terms of the specifics of the testing process. In this paper, we propose a new ...

Testing for uniform stochastic ordering via empirical likelihood

This paper develops an empirical likelihood approach to testing for the presence of uniform stochastic ordering (or hazard rate ordering) among univariate distributions based on independent random samples from each distribution. The proposed test statistic is formed by integrating a localized empirical likelihood statistic with respect to the empirical distribution of the pooled sample. The asy...

A New S-­test for Haplotype Analysis: Concordance and Discordance

A new test of inheritance, S, is proposed, which uses information from affected as well as unaffected siblings in the fam­ ily. The siblings are analyzed in terms of similarities of haplotypes. The distribution of the proposed S­test is derived under the null hypothesis of random inheritance. Mean and variance are obtained for the distribution. The test is then applied to data sets publ...